Psychedelic Drug Stocks +6% Last Week Vs. -13% Previous Week


Some BackgroundShares of clinical-stage companies developing treatments based on psychedelic compound-based drugs moved lower in early August after the U.S. Food and Drug Administration (FDA) rejected the use of MDMA for post-traumatic stress disorder (source) as submitted by a private company but noted that they were still supportive of psychedelic development given that psychedelic drugs showed initial promise as potential treatments for mood, anxiety and substance use disorders. Given that encouragement, they saw a 5.9% resurgence last week in the stock prices of the 4 largest companies specializing in psychedelic compound -based clinical-stage drug research and development.Our Psychedelic Compound -Based Clinical-Stage Drug Stocks PortfolioBelow are the performances of those four stocks for the week ending Sept. 13th and the previous week ending September 6th, in descending order, along with their area of focus, market capitalization, their prevailing short interest percentage (which is a measure of how many investors are betting that a stock’s price will fall further,) and any news contributing to the price change in the stock:

  • Compass Pathways (CMPS): up 9.4% w/e Sept. 13th; down 11.4% w/e Sept. 6th

    • Company Focus: CMPS is:

      • in the process of developing COMP360, a 
        psilocybin therapy that is in Phase III clinical trials for the treatment of treatment-resistant depression and
      • in Phase II clinical trials for the treatment of post-traumatic stress disorder and anorexia nervosa.
    • Market Capitalization: $496M
    • Short Interest: 6.8%
  • atai Life Sciences (ATAI): up 9.2% w/e Sept. 13th; down 8.5% w/e Sept. 6th

    • Company Focus: Develops and invests in various therapeutics to treat depression, anxiety, addiction, and other mental health disorders and has announced:

      • positive preliminary results from the Phase 1b trial of VLS-01, its proprietary oral trans-mucosal film formulation of mebufotenin that is applied to the buccal surface,
      • plans to initiate a Phase 2 study for the treatment of treatment-resistant depression and
      • plans to initiate a Phase 2 study (EMP-01) of an oral DMT for the treatment of social anxiety disorder by the end of FY’24
    • Market Capitalization: $218M
    • Short Interest: 5.7%
  • Mind Medicine (MNMD): up 8.4% w/e Sept. 13th; down 1.7% w/e Sept. 6th

    • Company Focus: lead product candidates include:

      • MM-120, which is in phase 2 for the treatment of generalized anxiety disorder and attention deficit hyperactivity disorder, and
      • MM-402, a R-enantiomer of 3,4-methylenedioxymethamphetamine (MDMA), which is in phase I clinical trials for the treatment of core symptoms of autism spectrum disorder.
    • Market Capitalization: $525M
    • Short Interest: 12.0%
  • GH Research (GHRS): up 0.9% w/e Sept. 13th; down 21.6% w/e Sept. 6th

    • Company Focus: engages in developing various therapies (see pipeline here) to treat psychiatric and neurological disorders and focuses on the development of mebufotenin therapies, the new International non-proprietary name for DMT, for the treatment of patients with treatment-resistant depression (TRD).
    • The company’s here for a mebufotenin inhalant has been very successful and is expected to end in the second half of this year and DMT is also being tested in a phase 2a trial for the treatment of postpartum depression (see details here).
    • Market Capitalization: $432M
    • Short Interest: 2.8%
      • After Plunging 18% in 4 Weeks, Here’s Why the Trend Might Reverse for GH Research
  • SummaryOn average, the above 4 stocks were up 5.9% in the week ending Sept. 13th vs. going down 13.1% w/e Sept. 6th (due primarily to GH Resources’  22% decline) and are now up 18.8% YTD.ConclusionThe psychedelic compound-based drug market is expected to triple over the next few years which should create many winning stocks in the years to come.More By This Author:Cannabis LP Stocks Were +6% Last Week Vs. -10% The Previous Week
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